{"id":365,"date":"2023-05-04T02:11:09","date_gmt":"2023-05-04T02:11:09","guid":{"rendered":"http:\/\/www.cynthiariginos.org\/wordpress\/?page_id=365"},"modified":"2023-05-04T02:30:34","modified_gmt":"2023-05-04T02:30:34","slug":"hisatake-ishida","status":"publish","type":"page","link":"http:\/\/www.cynthiariginos.org\/wordpress\/people\/hisatake-ishida\/","title":{"rendered":"Hisatake Ishida"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Hologenomic investigation of&nbsp;<em>in hospite<\/em>&nbsp;microbial symbionts in reef-building corals across the Great Barrier Reef<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/www.cynthiariginos.org\/wordpress\/wp-content\/uploads\/2023\/05\/IMAG0002-1024x850.jpg\" alt=\"\" class=\"wp-image-367\" width=\"-1777\" height=\"-1473\"\/><\/figure><\/div>\n\n\n<p>Reef-building corals harbour diverse communities of microbial symbionts that are critical to host health and survival. However, the complexity and unculturability of many coral microbiomes hamper the in-depth characterisation of compositional dynamics and diversity of microbial symbionts. To address these challenges, I will investigate population genomic data from ~1000 coral holobionts (i.e. hologenomic data) across the Great Barrier Reef in my PhD. These culture-independent data from high-throughput sequencing are dominated by host coral genomic sequences, yet they provide access to whole-genome data from&nbsp;<em>in hospite<\/em>&nbsp;microbial symbionts in coral tissues. Leveraging these extensive data, I aim to characterise the spatial genomic variation of the microbial community with respect to host coral genotypes and environmental gradients, and to reconstruct&nbsp;<em>de novo<\/em>&nbsp;symbiont genomes based on distinct data compositions of the microbial community. Overall, these studies will provide a molecular and mechanistic understanding of the functional roles that microbial communities play in the coral holobiont over large geographical scales.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hologenomic investigation of&nbsp;in hospite&nbsp;microbial symbionts in reef-building corals across the Great Barrier Reef Reef-building corals harbour diverse communities of microbial symbionts that are critical to host health and survival. However, the complexity and unculturability of<a class=\"moretag\" href=\"http:\/\/www.cynthiariginos.org\/wordpress\/people\/hisatake-ishida\/\"> Read more&hellip;<\/a><\/p>\n","protected":false},"author":1,"featured_media":366,"parent":102,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/pages\/365"}],"collection":[{"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/comments?post=365"}],"version-history":[{"count":3,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/pages\/365\/revisions"}],"predecessor-version":[{"id":376,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/pages\/365\/revisions\/376"}],"up":[{"embeddable":true,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/pages\/102"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/media\/366"}],"wp:attachment":[{"href":"http:\/\/www.cynthiariginos.org\/wordpress\/wp-json\/wp\/v2\/media?parent=365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}